Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6119349 | Journal of Autoimmunity | 2012 | 11 Pages |
Abstract
⺠EndoS significantly reduced the anti-type VII collagen-mediated tissue destruction. ⺠EndoS also hydrolyzed already-tissue-bound pathogenic autoantibodies. ⺠EndoS differentially modulated the expression of Fcγ receptors in lesional skin. ⺠Modulation of autoantibody glycolysation is a potential therapeutic option in severe autoimmune diseases.
Keywords
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Immunology
Authors
Misa Hirose, Katerina Vafia, Kathrin Kalies, Stephanie Groth, Jürgen Westermann, Detlef Zillikens, Ralf J. Ludwig, Mattias Collin, Enno Schmidt,