| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6119364 | Journal of Autoimmunity | 2012 | 14 Pages |
Abstract
⺠The constant region can affect autoantibody affinity and specificity. ⺠Class switch recombination may confer autoreactivity. ⺠Antibody isotype is instrumental in the nephritogenicity of antibodies to DNA. ⺠Enhanced kidney binding may contribute to the pathogenicity of IgG2a and IgG3.
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Authors
Yumin Xia, Rahul D. Pawar, Antonio S. Nakouzi, Leal Herlitz, Anna Broder, Kui Liu, Beatrice Goilav, Manxia Fan, Ling Wang, Quan-Zhen Li, Arturo Casadevall, Chaim Putterman,