Article ID Journal Published Year Pages File Type
6119377 Journal of Autoimmunity 2012 9 Pages PDF
Abstract
► IL-6 is required for post germinal center receptor editing that diminishes autoreactivity. ► IL-6 is regulated by estrogen with estrogen decreasing IL-6 production by B cells. ► These data suggest one mechanism for the increased humoral autoimmunity in women.
Keywords
Related Topics
Life Sciences Immunology and Microbiology Immunology
Preview
IL-6 contributes to an immune tolerance checkpoint in post germinal center B cells
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