| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6119379 | Journal of Autoimmunity | 2012 | 9 Pages |
Abstract
⺠Intermittent treatment with IL-12 reduced insulitis and prevented diabetes. ⺠Sustained production of the IL-17 contributed to the pathogenesis of autoimmune diabetes. ⺠Intermittent treatment with IL-12 enhanced the production of protective IFN-γ. ⺠IFN-γ induced by IL-12 strongly inhibits pathogenic IL-17-producing cells in NOD mice.
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Authors
Jun Zhang, Zhan Huang, Rui Sun, Zhigang Tian, Haiming Wei,