| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6119383 | Journal of Autoimmunity | 2012 | 10 Pages |
Abstract
⺠FOXP3 (TSDR) and CD3 (TLSDR) demethylation assays allow Treg cell quantification. ⺠TSDR/TLSDR ratio is altered in the majority of patients with immune dysregulation. ⺠IPEX-like syndromes share a quantitative but not functional defect of Treg cells.
Related Topics
Life Sciences
Immunology and Microbiology
Immunology
Authors
F. Barzaghi, L. Passerini, E. Gambineri, S. Ciullini Mannurita, T. Cornu, E.S. Kang, Y.H. Choe, C. Cancrini, S. Corrente, R. Ciccocioppo, M. Cecconi, G. Zuin, V. Discepolo, C. Sartirana, J. Schmidtko, A. Ikinciogullari, A. Ambrosi, M.G. Roncarolo,