| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6119403 | Journal of Autoimmunity | 2012 | 4 Pages |
Abstract
⺠Autoimmune thyroiditis (AIT) is characterized by a marked female preponderance. ⺠The reason for female preponderance in AIT is still unknown. ⺠We demonstrated that AIT women have a high frequency of blood X monosomic cells. ⺠We herein demonstrated that male with AIT progressively loss their Y chromosome. ⺠We surmise an instability of sex chromosome in AIT, with role in disease development.
Keywords
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Immunology
Authors
Luca Persani, Marco Bonomi, Ana Lleo, Simone Pasini, Fabiola Civardi, Ilaria Bianchi, Irene Campi, Palma Finelli, Monica Miozzo, Chiara Castronovo, Silvia Sirchia, M. Eric Gershwin, Pietro Invernizzi,