| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6119406 | Journal of Autoimmunity | 2012 | 7 Pages |
Abstract
⺠β2GPI-dependent aPL induce fetal loss/growth retardation in naïve pregnant mice. ⺠Histogenesis/organogenesis inhibition and not inflammation is involved in our model. ⺠The synthetic peptide TIFI competes with β2GPI binding and protects pregnant mice. ⺠Inhibition of β2GPI tissue expression represents an innovative therapeutic approach.
Related Topics
Life Sciences
Immunology and Microbiology
Immunology
Authors
Yeny Martinez de la Torre, Francesca Pregnolato, Fabio D'Amelio, Claudia Grossi, Nicoletta Di Simone, Fabio Pasqualini, Manuela Nebuloni, Pojen Chen, Silvia Pierangeli, Niccolò Bassani, Federico Ambrogi, Maria-Orietta Borghi, Annunciata Vecchi,