| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6119412 | Journal of Autoimmunity | 2012 | 9 Pages |
Abstract
⺠We observed substantial sex differences in survival following viral infections ⺠The differences were particularly striking with herpes simplex virus 1, HSV-1. ⺠Sex differences were independent of androgens and only partially attributable to estrogens. ⺠Enhanced male survival was mediated by sex differences in signaling through IFNabR and DAP12. ⺠This provides a robust model of sex-specific differences in innate immune responses.
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Authors
Theresa L. Geurs, Elaise B. Hill, Danna M. Lippold, Anthony R. French,