Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6121879 | Journal of Hospital Infection | 2016 | 17 Pages |
Abstract
Real-time polymerase chain reaction (PCR)-based approaches have not been assessed in terms of their ability to detect patients colonized by Acinetobacter baumannii during active surveillance. This prospective, double-blind study demonstrated that a real-time PCR assay had high sensitivity (100%) and specificity (91.2%) compared with conventional culture for detecting A. baumannii in 397 active surveillance samples, and provided results within 3 h. Receiver-operator curve analyses demonstrated that the technique has diagnostic accuracy of 97.7% (95% confidence interval 96.0-99.3%). This method could facilitate the rapid implementation of infection control measures for preventing the transmission of A. baumannii.
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Authors
P. Blanco-Lobo, V. González-Galán, M. GarcÃa-Quintanilla, R. Valencia, A. Cazalla, C. MartÃn, I. Alonso, P. Pérez-Romero, J.M. Cisneros, J. Aznar, M.J. McConnell,