Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6122360 | Journal of Hospital Infection | 2013 | 4 Pages |
Abstract
The aim of this retrospective study was to identify risk factors for hospital-acquired Clostridium difficile infection (HA-CDI) in orthopaedic patients. Thirty-two HA-CDI cases were each matched with two controls. Incidence rate was 0.33 cases per 1000 patient-days. Univariate analyses showed that surgery >24 h after admission, antibiotics for treatment, and proton pump inhibitors were associated with HA-CDI. Multivariate analyses revealed that surgery >24 h after admission was associated with HA-CDI. Patients hospitalized before surgery had a greater risk of HA-CDI, suggesting opportunities to reduce environmental exposure to C. difficile by timelier preoperative medical optimization in the outpatient setting.
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Authors
K.A. Campbell, M.S. Phillips, A. Stachel, J.A. III, S.A. Mehta,