Article ID Journal Published Year Pages File Type
6122833 Journal of Infection 2015 8 Pages PDF
Abstract
A state of hyporesponsiveness that resembles the concept of immunoparalysis in severe infection was observed in children with milder infections. Though IP-10, IL-2, IL-5 and IL-13 were confirmed as promising alternative biomarkers for discriminating controls with and without tuberculosis in this study, defective induction of these biomarkers by phytohemagglutinin in cases precluded their usefulness in overcoming quantiferon indeterminate results in the above-mentioned clinical conditions.
Related Topics
Life Sciences Immunology and Microbiology Applied Microbiology and Biotechnology
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