Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6122833 | Journal of Infection | 2015 | 8 Pages |
Abstract
A state of hyporesponsiveness that resembles the concept of immunoparalysis in severe infection was observed in children with milder infections. Though IP-10, IL-2, IL-5 and IL-13 were confirmed as promising alternative biomarkers for discriminating controls with and without tuberculosis in this study, defective induction of these biomarkers by phytohemagglutinin in cases precluded their usefulness in overcoming quantiferon indeterminate results in the above-mentioned clinical conditions.
Keywords
Related Topics
Life Sciences
Immunology and Microbiology
Applied Microbiology and Biotechnology
Authors
Mohamed Jeljeli, Valérie Guérin-El Khourouj, Agathe de Lauzanne, Marine Armand, Vibol Chhor, Béatrice Pédron, Stéphane Dauger, Jérôme Viala, Pierre Gressens, Albert Faye, Ghislaine Sterkers,