| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6123311 | Journal of Infection | 2013 | 10 Pages |
Abstract
Our data provide evidence that GR expression is progressively decreased in experimental sepsis and that dexamethasone has a decreased ability to translocate into the cell nucleus. This may explain why steroid treatment is only beneficial when administered early in sepsis and septic shock.
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Authors
Maria Bergquist, Merja Nurkkala, Christian Rylander, Erik Kristiansson, Göran Hedenstierna, Catharina Lindholm,