Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6123371 | Journal of Infection | 2013 | 11 Pages |
Abstract
Extensive sequestration is not a uniform requirement for severe paediatric malaria. The pathophysiology of hyperlactataemia and prostration appears to be unrelated to sequestered parasite biomass. Different mechanisms may underlie different severe malaria syndromes, and different therapeutic strategies may be required to improve survival.
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Authors
Aubrey J. Cunnington, Michael T. Bretscher, Sarah I. Nogaro, Eleanor M. Riley, Michael Walther,