Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6123473 | Journal of Infection | 2007 | 6 Pages |
Abstract
New T cell-based blood tests for tuberculosis infection could improve diagnosis of tuberculosis but their clinical utility remains unknown. We describe the role of the ELISpot test in the diagnostic work-up of 13 patients presenting with suspected tuberculosis in routine practice. Of the seven patients with a final diagnosis of active tuberculosis, all were positive by ELISpot including three with false-negative tuberculin skin test results. Rapid determination of tuberculosis infection by ELISpot accelerated the diagnosis of tuberculosis, enabling early treatment initiation.
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Authors
Sarah Gooding, Oni Chowdhury, Tim Hinks, Luca Richeldi, Monica Losi, Katie Ewer, Kerry Millington, Ruba Gunatheesan, Stefania Cerri, Jeremy McNally, Ajit Lalvani,