Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6123572 | Journal of Infection and Chemotherapy | 2015 | 5 Pages |
Abstract
A case of disseminated nontuberculous mycobacteria(l) (NTM) infection in a patient with positive neutralizing anti-interferon-γ (IFN-γ) autoantibodies involving bone, bronchus, systemic lymph nodes, and skin is reported. The causative NTMs were two different strains: Mycobacterium gordonae, which rarely causes true disease, and Mycobacterium mantenii, which is extremely rare. Anti-mycobacterial treatment successfully ameliorated all disseminated lesions. Although the concentration of anti-IFN-γ autoantibodies increased during the pre-treatment period, it gradually decreased after anti-mycobacterial treatment was started.
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Authors
Isano Hase, Kozo Morimoto, Takuro Sakagami, Yuko Kazumi, Yoshiki Ishii, Jakko van Ingen,