Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6124399 | Osteoarthritis and Cartilage | 2016 | 9 Pages |
Abstract
We demonstrate that anti-NGF antibody treatment attenuates OA pain behaviour despite permitting cartilage damage and synovitis. Indirect effects on subchondral bone remodelling may contribute to the analgesic effects of NGF blockade.
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Authors
L. Xu, L.N. Nwosu, J.J. Burston, P.J. Millns, D.R. Sagar, P.I. Mapp, P. Meesawatsom, L. Li, A.J. Bennett, D.A. Walsh, V. Chapman,