| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6124446 | Osteoarthritis and Cartilage | 2016 | 9 Pages |
Abstract
We provide evidence that Dkk3 is upregulated in OA and may have a protective effect on cartilage integrity by preventing proteoglycan loss and helping to restore OA-relevant signaling pathway activity. Targeting Dkk3 may be a novel approach in the treatment of OA.
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Authors
S.J.B. Snelling, R.K. Davidson, T.E. Swingler, L.T.T. Le, M.J. Barter, K.L. Culley, A. Price, A.J. Carr, I.M. Clark,