Article ID Journal Published Year Pages File Type
6124515 Osteoarthritis and Cartilage 2016 10 Pages PDF
Abstract
Gene expression changes in damaged cartilage suggested a signature non-chondrogenic response of altered matrix protein and secreted proteinase expression. There was evidence of a damage response in this late OA cartilage, which surprisingly showed features detected experimentally in the early response of cartilage to mechanical overload. PhenomeExpress analysis identified a hub of DEGs linked by a core of four differentially regulated TFs.
Related Topics
Health Sciences Medicine and Dentistry Immunology, Allergology and Rheumatology
Authors
, , , , , ,