Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6124519 | Osteoarthritis and Cartilage | 2016 | 9 Pages |
Abstract
Cathepsin K cleaves triple helical collagen by erosion from the N-terminus and with subsequent progressive cleavages. The liberated fragments can be detected in osteoarthritic cartilage and may represent useful biomarkers for disease activity.
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Authors
J.S. Mort, F. Beaudry, K. Théroux, A.A. Emmott, H. Richard, W.D. Fisher, E.R. Lee, A.R. Poole, S. Laverty,