Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6124566 | Osteoarthritis and Cartilage | 2016 | 9 Pages |
Abstract
Outcomes of in vivo CTa in human OA knees correlate well with sGAG content. Outcomes of CTa also slightly correlate with cartilage collagen content. Since outcomes of CTa are mainly sGAG dependent and despite the fact that further validation using hyaline cartilage of other joints with different biochemical composition should be conducted, CTa may be suitable as quantitative imaging biomarker to estimate cartilage sGAG content in future clinical OA research.
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Authors
J. van Tiel, M. Siebelt, M. Reijman, P.K. Bos, J.H. Waarsing, A.-M. Zuurmond, K. Nasserinejad, G.J.V.M. van Osch, J.A.N. Verhaar, G.P. Krestin, H. Weinans, E.H.G. Oei,