Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6124570 | Osteoarthritis and Cartilage | 2016 | 37 Pages |
Abstract
The meniscus demonstrates resistance to OP1 stimulation in OA and in the presence of inflammatory mediators. MAPK-mediated Smad1 linker phosphorylation is a possible mediator of the loss of anabolic extracellular matrix production in the inflammatory cytokine affected meniscus.
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Authors
K.S. Vanderman, R.F. Loeser, S. Chubinskaya, A. Anderson, C.M. Ferguson,