Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6124629 | Osteoarthritis and Cartilage | 2015 | 9 Pages |
Abstract
These data clearly describe significant associations between KL grade, JSW, pain and BMI in patients with symptomatic knee OA. KL grade, BMI and WOMAC pain were diagnostically associated with OA based on JSW but only KL-score and pain in a non-linier fashion was prognostic. 50% of patients did not progress more than MSC, highlighting the importance for identification of structural progressors and the phenotypes associated with these. These results suggest that disease phenotypes, rather than disease status, are responsible for disease progression.
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Authors
M.A. Karsdal, A. Bihlet, I. Byrjalsen, P. Alexandersen, C. Ladel, M. Michaels, J.R. Andersen, B.J. Riis, V. Kraus, A.C. Bay-Jensen, C. Christiansen,