Article ID Journal Published Year Pages File Type
6124654 Osteoarthritis and Cartilage 2015 10 Pages PDF
Abstract
Our work suggests roles for XBP1 in regulating chondrocyte proliferation and the timing of mineralization during endochondral ossification, findings which have implications for both skeletal development and disease.
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Related Topics
Health Sciences Medicine and Dentistry Immunology, Allergology and Rheumatology
Preview
Cartilage-specific ablation of XBP1 signaling in mouse results in a chondrodysplasia characterized by reduced chondrocyte proliferation and delayed cartilage maturation and mineralization
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