Article ID Journal Published Year Pages File Type
6124748 Osteoarthritis and Cartilage 2015 9 Pages PDF
Abstract
Depletion of SIRT6 in human chondrocytes caused increased DNA damage and telomere dysfunction, and subsequent premature senescence. These findings suggest that SIRT6 plays an important role in the regulation of senescence of human chondrocytes.
Keywords
Related Topics
Health Sciences Medicine and Dentistry Immunology, Allergology and Rheumatology
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Depletion of SIRT6 causes cellular senescence, DNA damage, and telomere dysfunction in human chondrocytes
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