Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6124908 | Osteoarthritis and Cartilage | 2015 | 7 Pages |
Abstract
This study demonstrates that biochemical markers of joint tissue damage increase shortly after a single joint bleed, both in humans with established hemophilic arthropathy (HA) and in an animal model of joint damage upon a first joint bleed. Biomarkers might be useful in monitoring the impact of a joint bleed and in evaluation of treatment of such bleeds.
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Authors
L.F.D. van Vulpen, M.E.R. van Meegeren, G. Roosendaal, N.W.D. Jansen, J.M. van Laar, R.E.G. Schutgens, S.C. Mastbergen, F.P.J.G. Lafeber,