Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6124932 | Osteoarthritis and Cartilage | 2015 | 10 Pages |
Abstract
In localized, repeated synovitis in rats, sustained release of TCA following a single IA injection of FX006 significantly prolonged analgesia relative to TCA IR and significantly improved histological scores with no adverse effect on the HPA axis. Since synovitis can contribute to the pathophysiology of multiple joint diseases such as osteoarthritis (OA), RA and gout, FX006 may be an important treatment option for these conditions.
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Authors
A. Kumar, A.M. Bendele, R.C. Blanks, N. Bodick,