Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6124948 | Osteoarthritis and Cartilage | 2014 | 10 Pages |
Abstract
Chondrocyte expansion and de-differentiation impaired the cell response, resulting in inferior cartilage repair in vitro. With TGF-β3 pre-treatment, MSCs were able to undergo sustained chondrogenic differentiation and exhibited superior matrix deposition and integration compared to de-differentiated chondrocytes.
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Authors
L. Rackwitz, F. Djouad, S. Janjanin, U. Nöth, R.S. Tuan,