| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6124956 | Osteoarthritis and Cartilage | 2014 | 11 Pages |
Abstract
These data indicate that an exaggerated inflammatory environment may decrease BMP-2/ACS-induced bone mass in vivo by suppressing BMP-2-induced osteoblastic differentiation and by increasing the number or activity of osteoclasts. The negative role of exaggerated inflammation deserves consideration for future clinical use of BMP-2 in inducing bone regeneration.
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Authors
R.-L. Huang, Y. Yuan, J. Tu, G.-M. Zou, Q. Li,