| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6125030 | Osteoarthritis and Cartilage | 2015 | 9 Pages |
Abstract
This study demonstrates that IRAP treatment administered during acute phase of cartilage impact injury increases expression levels of miR-140, miR-125b, and miR-27b in cartilage, indicating increased inhibition of their respective matrix-degrading enzymes. Clinically, these findings support the potential of IRAP treatment as an early intervention strategy for the prevention of cartilage degeneration after impact injury.
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Authors
A.A. Genemaras, T. Reiner, C.-Y. Huang, L. Kaplan,