| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6125062 | Osteoarthritis and Cartilage | 2015 | 12 Pages |
Abstract
Our results indicate that meniscal tissue is more susceptible to adipokine-stimulated catabolism than is cartilage. Resistin had the strongest effect of the adipokines tested, inducing sGAG release in both tissues and depleting sGAG content in meniscus. These results suggest that increased adipokine levels due to obesity or joint injury may alter the mechanical integrity of the knee joint through biological pathways.
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Authors
J.F. Nishimuta, M.E. Levenston,