Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6125065 | Osteoarthritis and Cartilage | 2015 | 6 Pages |
Abstract
T-2 toxin could up-regulate NOD2 expression via ROS/NF-κB pathway and activate NOD2 signaling pathway. The up-regulated NOD2 would affect the metabolism gene expressions and MMP activity in chondrocytes via RIPK2 and TBK1. The findings add new insights into understanding NOD2 effects on chondrocytes treated with T-2 toxin.
Keywords
Related Topics
Health Sciences
Medicine and Dentistry
Immunology, Allergology and Rheumatology
Authors
J. Xu, C. Jiang, W. Zhu, B. Wang, J. Yan, Z. Min, M. Geng, Y. Han, Q. Ning, F. Zhang, J. Sun, L. Meng, S. Lu,