Article ID Journal Published Year Pages File Type
6125467 Osteoarthritis and Cartilage 2013 9 Pages PDF
Abstract
A significantly greater likelihood of radiological progression of knee OA was associated with a commonly occurring IL1RN haplotype that could be tagged by three IL1RN SNPs (rs419598, rs9005, rs315943). Interactions were also observed between IL1RN gene variants and BMI relative to OA progression. This suggests that IL1RN gene markers may be useful in stratifying patients for medical management and drug development.
Keywords
Related Topics
Health Sciences Medicine and Dentistry Immunology, Allergology and Rheumatology
Preview
IL-1 receptor antagonist gene as a predictive biomarker of progression of knee osteoarthritis in a population cohort
Authors
, , , , , , ,