Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6125616 | Osteoarthritis and Cartilage | 2010 | 8 Pages |
Abstract
Our data reveal that clenbuterol-induced skeletal muscle hypertrophy is unable to mimic the beneficial clinical effects of increased musculature derived through targeted strength training in humans, in a rodent model of MNX-induced OA. In addition we observed fibre-type switching to “slow twitch” in the quadriceps muscle during the induction of OA that warrants further investigation as to its relationship to joint stability.
Keywords
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Authors
D.P. Tonge, S.W. Jones, T. Parr, R. Bardsley, M. Doherty, R.A. Maciewicz,