| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6125646 | Osteoarthritis and Cartilage | 2010 | 9 Pages |
Abstract
These findings implicate p38 and ERK mitogen activated protein kinases (MAPKs) in the post-injury spread of cartilage degeneration and suggest that the risk of post-traumatic osteoarthritis (PTOA) following joint trauma could be decreased by blocking their activities, which might be involved in up-regulating expressions of MMP-13, ADAMTS-5, and TNF-α.
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Authors
L. Ding, E. Heying, N. Nicholson, N.J. Stroud, G.A. Homandberg, J.A. Buckwalter, D. Guo, J.A. Martin,