Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6125649 | Osteoarthritis and Cartilage | 2010 | 8 Pages |
Abstract
These data indicate that GW405833 reduces the mechanosensitivity of afferent nerve fibres in control joints but causes nociceptive responses in OA joints. The observed pro-nociceptive effect of GW405833 appears to involve TRPV1 receptors.
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Authors
N. Schuelert, C. Zhang, A.J. Mogg, L.M. Broad, D.L. Hepburn, E.S. Nisenbaum, M.P. Johnson, J.J. McDougall,