Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6125915 | Seminars in Immunology | 2011 | 11 Pages |
Abstract
⺠HLA sensitization can be a barrier to successful transplantation of all solid organs. ⺠ABO and HLA incompatible transplants now possible after antibody depletion protocols. ⺠Knowing antibody strength helps stratify risk of antibody-mediated rejection. ⺠Lag in isohemagglutinin development offers unique window for neonatal heart transplant. ⺠Complex and layered humoral responses preclude the clinical application of xenotransplantation.
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Authors
Robert A. Montgomery, Emanuele Cozzi, Lori J. West, Daniel S. Warren,