| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6125953 | Transplant Immunology | 2016 | 6 Pages |
Abstract
We demonstrated increased levels of immunoglobulins and complement proteins dominantly present in rCLAD. This leads to the belief that antibodies and AMR might play a more important role in rCLAD compared to BOS. Therefore, anti B-cell therapy could offer beneficial therapeutic effects in patients diagnosed with rCLAD, which needs further research.
Keywords
FEV1BOSTLCAMRRASFVCLTXBALDSAantibody mediated rejectiondonor specific antibodiesHuman leukocyte antigenHLAchronic lung allograft dysfunctioncomputed tomographyForced expiratory volume in 1 sBronchiolitis obliterans syndromerestrictive allograft syndromebroncho-alveolar lavageforced vital capacityTotal lung capacitybroncho-alveolar lavage fluidCLADLung transplantation
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Authors
Elly Vandermeulen, Stijn E. PhD, Hannelore Bellon, David MD, Elise Lammertyn, Sandra Claes, Jennifer PhD, Estafania Ugarte-Berzal, Dominique PhD, Marie-Paule MD, PhD, Dirk E. MD, PhD, Ghislain MD, PhD, Geert M. MD, PhD, Robin MD, PhD, Bart M. PhD,