Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6125997 | Transplant Immunology | 2014 | 9 Pages |
Abstract
Increased Treg frequencies and reduced HCV-NS3 antigen-specific responses recovered after viral eradication in post-OLT chronic hepatitis C patients. Reduced Tr1 frequencies were associated with hepatitis activity control, which may facilitate controlling chronic hepatitis C in patients after OLT.
Keywords
LPSTr1CD4 + T cellsTh1PNALTELISPOTCHCOLTRPMIALTFITCPBSFOXP3PBMCSVRAlanine aminotransferaseinterferonIFNinterleukinforkhead box P3Peripheral blood mononuclear cellDendritic cellfluorescein isothiocyanatelipopolysaccharideRoswell Park Memorial InstitutePhosphate-buffered salineenzyme-linked immunosorbent spotchronic hepatitis CHepatitis C virusHCVSustained viral responseorthotopic liver transplantation
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Authors
Masashi Utsumi, Akinobu Takaki, Yuzo Umeda, Kazuko Koike, Stephanie C. Napier, Nobukazu Watanabe, Hiroshi Sadamori, Susumu Shinoura, Ryuichi Yoshida, Daisuke Nobuoka, Tetsuya Yasunaka, Eiichi Nakayama, Kazuhide Yamamoto, Toshiyoshi Fujiwara,