Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6126077 | Transplant Immunology | 2012 | 5 Pages |
Abstract
⺠Directly targets terminally differentiated, antibody-producing plasma cells. ⺠Effectively reduces HLA-antibody levels in antibody-mediated rejection. ⺠Does not alter preformed HLA-antibody levels and specificity in sensitized patients. ⺠Does not impair protective immunity. ⺠Requires activated plasma cells to induce apoptosis and alter antibody production.
Keywords
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Authors
Martina Guthoff, Barbara Schmid-Horch, Katja C. Weisel, Hans-Ulrich Häring, Alfred Königsrainer, Nils Heyne,