Article ID Journal Published Year Pages File Type
6126077 Transplant Immunology 2012 5 Pages PDF
Abstract
► Directly targets terminally differentiated, antibody-producing plasma cells. ► Effectively reduces HLA-antibody levels in antibody-mediated rejection. ► Does not alter preformed HLA-antibody levels and specificity in sensitized patients. ► Does not impair protective immunity. ► Requires activated plasma cells to induce apoptosis and alter antibody production.
Related Topics
Life Sciences Immunology and Microbiology Immunology
Authors
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