Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6127494 | Acta Tropica | 2014 | 10 Pages |
Abstract
- The mitochondrial localization of HslVU is definitely established in trypanosomatids.
- HslV is essential for the bloodstream forms of Trypanosoma brucei, like for procyclics.
- Contrasting with previous works, HslU1 also appears essential to parasite survival.
- HslV and HslU1 appear to be involved in the control of different cell cycle events.
- These data validate HslVU as a promising drug target against these parasites.
Related Topics
Life Sciences
Immunology and Microbiology
Parasitology
Authors
Diane-Ethna Mbang-Benet, Yvon Sterkers, Christelle Morelle, Ndeye-Mathy Kebe, Lucien Crobu, Pierre Portalès, Olivier Coux, Jean-François Hernandez, Sabrina Meghamla, Michel Pagès, Patrick Bastien,