| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6127731 | Acta Tropica | 2013 | 7 Pages |
Abstract
⺠P. falciparum CNP and SNP containing genes may influence key parasite phenotypes. ⺠Pfmdr-1, gch1 or novel gene amplifications were absent in P. falciparum isolates. ⺠Mutations in Pfmdr-1 and Pfcrt genes were not associated with clinical outcome. ⺠Continued surveillance for changes in copy number and SNPs is essential. ⺠P. falciparum phenotypic variation may have a role in parasite virulence mechanisms.
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Authors
Mpungu Steven Kiwuwa, Justus Byarugaba, Mats Wahlgren, Fred Kironde,