Article ID Journal Published Year Pages File Type
6127755 Acta Tropica 2012 14 Pages PDF
Abstract
► Chandipura Virus (CHPV) infestation shows symptoms similar to encephalitis and is fatal. ► Children are major patient group with high mortality rates in India. ► Detection of viral RNA is done by nested RT-PCR rather by IgM anti-CHPV antibodies. ► Intracranial administration of P gene siRNA protects mice from CHPV infection. ► Vero cell based vaccine candidate against CHPV was developed and evaluated for immunogenicity in mice.
Related Topics
Life Sciences Immunology and Microbiology Parasitology
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