Article ID Journal Published Year Pages File Type
6127930 Acta Tropica 2012 6 Pages PDF
Abstract
► We used C57BL/6 mice infected with Schistosoma japonicum to examine the role of poly I:C in liver fibrosis. ► Poly I:C treatment significantly attenuated hepatic fibrosis caused by the eggs. ► Poly I:C treatment increased mRNA expression of Th1 cytokines, IL-10, NKG2D, and TRAIL in the liver of infected mice. ► Poly I:C treatment decreased intrahepatic Th2 cytokine mRNA expression.
Related Topics
Life Sciences Immunology and Microbiology Parasitology
Authors
, , , , , , , ,