| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6127978 | Acta Tropica | 2013 | 9 Pages |
Abstract
⺠We established a SYBR Green real-time qPCR assay to quantify T. cruzi load in blood. ⺠Chronic Chagas cardiomyopathy patients from the BENEFIT trial were evaluated. ⺠The median parasitic load found in Brazilian patients was 0.1 parasite equivalents/mL. ⺠Chronic Chagas disease patients from Colombia and Argentina yielded parasitemia values roughly 20 times higher than patients from Brazil. ⺠qPCR is useful to detect and quantify low parasite burden in chronic Chagas disease.
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Authors
Otacilio C. Moreira, Juan David RamÃrez, Elsa Velázquez, Myllena F. A. Dias Melo, Carolina Lima-Ferreira, Felipe Guhl, Sergio Sosa-Estani, Jose Antonio Marin-Neto, Carlos A. Morillo, Constança Britto,