Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6128270 | Acta Tropica | 2011 | 6 Pages |
Abstract
⺠Combination of ketoconazole and miltefosine with immunomodulator, picroliv against VL. ⺠Combination of dugs showed enhanced antileishmanial efficacy in comparison to individual drug. ⺠Ketoconazole + miltefosine showed significant rise in phagocytosis index and production of ROS H2O2 and NO. ⺠Picroliv is inactive but helps in up regulation of cellular proliferative response. ⺠Picroliv in combination with ketoconazole + miltefosine appears to be a good strategy for treatment.
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Authors
Nishi Shakya, Shraddha A. Sane, Preeti Vishwakarma, Preeti Bajpai, Suman Gupta,