| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6128271 | Acta Tropica | 2011 | 5 Pages |
Abstract
⺠The relationship between sterol inhibition and cholesterol uptake by Leishmania was evaluated. ⺠L. amazonensis under pharmacological ergosterol inhibition accumulates more cholesterol. ⺠The higher levels of cholesterol in treated L. amazonensis correlate to higher LDL endocytosis. ⺠L. amazonensis was up to 50% more susceptible to sterol inhibitors in the absence of exogenous cholesterol.
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Authors
Valter Viana Andrade-Neto, Nuccia Nicole Theodore Cicco, Edézio Ferreira Cunha-Junior, Marilene Marcuzzo Canto-Cavalheiro, Georgia Correa Atella, Eduardo Caio Torres-Santos,