Article ID Journal Published Year Pages File Type
6128325 Acta Tropica 2011 4 Pages PDF
Abstract
► Absence of homologs of Plasmodium cytochrome P450 (CYP), i.e., CYP1A, 2A, 2B and 2E enzymes. ► Absence of CYP2B1/B2 gene in P. falciparum using Northern analysis with a rat CYP2B1/B2 probe. ► We investigate for the presence of a homologous protein of the mammalian cytochrome P450 CYP2B1/B2 in Plasmodium falciparum. ► The analysis failed to identify homologs to CYP1A, 2A, 2B and 2E enzymes. ► Plasmodium does not contain identifiable sequences with known human CYP enzymes.
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Life Sciences Immunology and Microbiology Parasitology
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