Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6128403 | Acta Tropica | 2008 | 4 Pages |
Abstract
From 2001 to 2006, about one-third of the residents aged 5-65 years were selected as the subjects in a schistosome-endemic village located in Jiangxi Province, China. Every 1 year, all participants were analyzed by the Kato-Katz parasitologic examination and indirect hemagglutination assay (IHA). Statistical analysis of the results showed the k indices ranged from 0.250 to 0.347 between the two methods. Assuming the Kato-Katz results as the gold standard reference, the specificity of the IHA was from 60% to 77%, the positive predictive value of this method was from 19% to 30%, and its sensitivity and negative predictive value were more than 97%. The IHA method is unsuitable for individual screening in endemic community with relatively high prevalence (e.g. with >10% or more prevalence). A search for a better diagnostic test that can be applied in field situations in China is essential and should be given high priority.
Keywords
Related Topics
Life Sciences
Immunology and Microbiology
Parasitology
Authors
Yi-Biao Zhou, Mei-Xia Yang, Po Tao, Qiu-Lin Jiang, Gen-Ming Zhao, Jian-Guo Wei, Qing-Wu Jiang,