| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6133151 | Journal of Virological Methods | 2015 | 5 Pages |
Abstract
High-risk human papillomavirus (HPV) detection and genotyping is critical for cervical cancer screening. Testing of 967 cervical cytology specimens in PreservCyt preservative revealed similar positivity rates for HC2 (13.8%) and APTIMA HPV (AHPV) tests (13.5%, p = 0.89) and high overall agreement (94.6%, κ = 0.77). A trend towards higher HPV16 positivity rates by the Cobas HPV test (23.0%, 26/113) compared to the AHPV genotyping assay (19.5%, 22/113; p = 0.125) was noted. No cross-contamination was detected with AHPV in a challenge experiment.
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Authors
Michael T. Pyne, Camille L. Hamula, Keith Tardif, Christian Law, Robert Schlaberg,