Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6134373 | Journal of Virological Methods | 2013 | 7 Pages |
Abstract
⺠A highly sensitive method based on the Q-Invader technology was developed. ⺠The assay specifically detects mutations at aa 70/91 in the HCV-1b core region. ⺠The relative ratios of the minor variant were detected in 1% of total. ⺠All of the mutations that were detected by direct sequencing were also detected. ⺠The minor variants found by this assay were confirmed by PCR with specific primers.
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Authors
Kenichi Tadokoro, Mariko Kobayashi, Fumitaka Suzuki, Chie Tanaka, Toshikazu Yamaguchi, Makoto Nagano, Toru Egashira, Hiromitsu Kumada,